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Crestor | Heart Disease Drug

Crestor® (generic name: rosuvastatin) is a widely-prescribed drug from the class of statins, used to treat high cholesterol and to prevent heart disease. Crestor, made by AstraZeneca, and was FDA-approved and launched in 2003 and was prescribed to more than four million patients by the end of 2004.

When Crestor was first before the FDA (Food and Drug Administration) for approval, the process was delayed due to safety concerns. These concerns included kidney damage, as well as a potentially-fatal condition known as rhabdomyolysis. Rhabdomyolysis is a breakdown of muscle fibers which results in kidney damage due to muscle content entering the bloodstream.

Since its introduction, there have been reports of kidney damage, renal failure, rhabdomyolysis and at least one death.

The most common side-effects of alendronate are:

• Weakness
• Nausea, stomach pain, constipation, diarrhea
• Sore throat, runny or stuffy nose
• Headache
• Pain or burning when you urinate.

Less common, but more severe side-effects are listed as:

• Muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine
• Urinating more or less than usual, or not at all
Jaundice (yellowing of the skin or eyes)
• Chest pain
• Swelling in your hands or feet

Signs of possible rhabdomyolysis are:

• Abnormal urine color (dark, red, or cola colored)
• Muscle tenderness
• Weakness of the affected muscle(s)
• Generalized weakness
• Muscle stiffness or aching (myalgia)
• Weight gain (unintentional)
• Seizures
• Joint pain
• Fatigue

If you believe your Crestor use has put you or a loved one in danger, please fill out our Case Review Contact Form to the right on this page to find out what your case is worth.